![]() Additionally, TJMs can be attenuated using antiparkinsonian agents including L-DOPA, DA agonists, anticholinergics, and adenosine A2A antagonists. Tremulous jaw movements (TJMs) are defined as “rapid vertical deflections of the lower jaw that resemble chewing but are not directed at any particular stimulus.” TJMs occur in a frequency range of 3-7 Hz and are induced by a number of pharmacological manipulations that parallel those seen in human Parkinsonism including dopamine (DA) depleting agents, DA antagonists, and cholinomimetic administration. Parkinsonian resting tremor can be modeled in rodents using the tremulous jaw movement model. ![]() ![]() Show more Parkinsonism is a movement disorder characterized by several cardinal motor symptoms: resting tremor, akinesia, bradykinesia, rigidity, and postural instability. Until the next time, if I see a robot wanting me to follow him into the future, I am going to take him up on his offer.Parkinsonism is a movement disorder characterized by several cardinal motor symptoms: resting tremor, akinesia, bradykinesia, rigidity, and. The robot would win every time hands down.) If I did not have to go back to work, I might have asked him about the future, including the future of winter coats. (As a side note, in my book, there can be no battle against a robot. He wanted people to follow him to the future.Īfter seeing that sight, why would my wearing a winter coat make any difference? Suddenly, my quandary with to wear a winter coat or not to wear one was replaced by a person wearing something else-a robot costume. ![]() Not a pleasant experience whatsoever but my outlook took an amusing change when I saw a guy dressed up as a robot. As people passed me without their winter coats, the one I wore felt like someone was trying to smother me to death. I finally got the “no winter coat needed” memo when I strolled down Nicollet Mall over the lunch hour. A spring coat would have been sufficient. On the hand, with today’s high of 61 degrees, it does mean that a winter coat is not a necessity. In such frigid conditions, there is no room for tremulous behavior. I know this might seem extreme but when the temperatures can drop to below zero degrees Fahrenheit in a manner of hours, dressing appropriately is essential. In Minnesota, not knowing the weather forecast can mean the difference between life and death. Because I did not watch the Sunday night news, I was not informed on what the current weather conditions were going to be like. ![]() When I woke up this morning, I got ready like it was another day of work. Unfortunately, today was such a day I should have asked myself this hard-hitting query. There are days in this beautiful state where you have to ask yourself: to wear or not to wear a winter coat, that is the question. If you have ever lived in Minnesota, you might know where I am going with this entry. ![]()
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